Genetic Rant & Roll – The Miniseries: Part 8

Lin/Linda here again to finish up my report.

On to the graph.  I AM sensitive to zinc!  Gerry told me never EVER to take zinc.  He said that I am the ‘poster child’ and why they really want to do these tests. I don’t have AMD now but this gives me VALUABLE information if I do develop it.

It shows what happened to the ‘average’ participants in the AREDS study (first one) who had the same genotype as me in regard to CFH & ARMS2 only. Each line shows one of the 4 treatment groups in the study (the key is below): placebo is solid blue line, antioxidant is dashes in red line, AREDS F(ormula – the one with zinc) is dotted blue line,  and just zinc is green line with dots).  What it shows is that the zinc & AREDS Formula with zinc groups progressed to advanced AMD faster than the other two groups!  Yikes! Scary!

 

 

 

If you look back at Sue’s graph, participants in the AREDS study progressed at the same rate over the 7 years of the study no matter what group they were in.  So because of her CFH and ARMS2 genes, none of the study treatments – antioxidants alone or AREDS Formula with zinc or zinc alone – would have helped.  Remember, she’s sadly already at advanced AMD.  For a person who has financial constraints, knowing this in the early stage could have saved quite a bit of money spend on supplements.

 

So that’s the end of the analysis of our reports.  Most of the people who have genetic testing will also get a 10 year prognosis which is used to advise their eye professional as to what their care plan should be.  That’s in the next page.

Click here to review the research that supports the genetic testing by ArcticDX.

Click here to review the findings about the dangers of zinc for those with a specific genotype.

Click here for other sources of genetic testing for AMD through the US National Center for Biotechnology Information (NCBI), a division of the National Institute of Health. This is their Genetic Testing Registry with labs around the world not only in the US.

Next: Genetic Rant & Roll – The Miniseries: Part 9

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