A Quick Explanation of Genotypes

This is a VERY simplified explanation, one to help understand the research from this point forward.

  • Genes are broken into markers called alleles and alleles have codes which can indicate a person’s lifetime risk of vision loss (much more complicated than that).
  • For this purpose, the risk codes are: 0 is no risk, 1 is some risk, 2 is high risk.
  • For the gene CFH, the abbreviation is C.  If a person has no risk on the gene CFH, that’s C0, some risk is C1, high risk C2.
  • For the gene ARMS2, the abbreviation is A.  If I person has no risk on the gene ARMS2, that’s A0, some risk A1, high risk A2.
  • Those codes are put together to express a genotype.
  • For example, if the genotype is C2A1 that means on the CFH gene there are 2 risk alleles and on the ARMS2 gene that’s 1 risk allele.

Back to Eye Vitamins: Part 6 – What’s all the talk about zinc? Part 2

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